Liferature: Writing Life with Protein Language Models

“At the threshold where language models write proteins and biological architectures emerge from code, literature faces its most profound transformation since the invention of writing.” Protein language models “don’t just analyze proteins, they create them” — a shift “from representing to creating” that marks the move from literature to liferature, “the writing of life itself, not merely its description.” Traces the lineage from ProGen and ProtGPT2 through AlphaFold to ESM3.

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